Monterrey is a large city with a wide variety of transportation options. Bus, plane, or personal car are the most practical ways to get to Monterrey.
By car
Monterrey is about 200km south of the U.S./Mexico border. The most common border crossings, both in South Texas, used to get to Monterrey are Laredo/Nuevo Laredo and McAllen-Hidalgo/Reynosa. The travel time from either Reynosa or Nuevo Laredo is about two hours. Many regios As residents of Monterrey are nicknamed drive to San Antonio and all points north through Puente Colombia outside of Nuevo Laredo. This can be attributed to safety concerns following press coverage of Nuevo Laredo's international drug trade violence.
From points in the United States, take Interstate 35 south. The highway ends at International Bridge 2 in Laredo. The Aduana office for handling vehicle import paperwork is on the river road in between Bridge 1 and Bridge 2. Mexican auto insurance can also be purchased there. From Nuevo Laredo, take Mexico Highway 85 south and it brings you right into Monterrey.
Guia Roji maps to Mexico are indispensible for drivers in Mexico. You can buy them online ahead of time, or they are sold in every Sanborns store in Mexico. You will need a map to drive in Monterrey because the city is large and complex.